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Proniosomal gel-derived niosomes: an approach to sustain and improve the ocular delivery of brimonidine tartrate; formulation, in-vitro characterization, and in-vivo pharmacodynamic study
Brimonidine tartrate (BRT) is a hydrophilic α(2) adrenergic agonist used for the treatment of glaucoma. Glaucoma is an ocular disease affecting the anterior segment of the eye requiring lifetime treatment. Owing to the obstacles facing ocular delivery systems and hydrophilicity of BRT, frequent admi...
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| Publicado no: | Drug Deliv |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6534210/ https://ncbi.nlm.nih.gov/pubmed/31090464 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2019.1609622 |
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