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A Synthetic Gene Circuit for Self-Regulating Delivery of Biologic Drugs in Engineered Tissues

Transient, resolving inflammation plays a critical role in tissue repair and regeneration. In the context of joint disease, however, chronic inflammation following injury or with osteoarthritis can lead to irreversible articular cartilage degradation and joint pain. Developing tissue engineering str...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Tissue Eng Part A
Hauptverfasser: Pferdehirt, Lara, Ross, Alison K., Brunger, Jonathan M., Guilak, Farshid
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mary Ann Liebert, Inc., publishers 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6533793/
https://ncbi.nlm.nih.gov/pubmed/30968743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ten.tea.2019.0027
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