Identification of dynamic glucocorticoid-induced methylation changes at the FKBP5 locus

BACKGROUND: Epigenetic mechanisms may play a major role in the biological embedding of early-life stress (ELS). One proposed mechanism is that glucocorticoid (GC) release following ELS exposure induces long-lasting alterations in DNA methylation (DNAm) of important regulatory genes of the stress res...

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Detalhes bibliográficos
Publicado no:Clin Epigenetics
Main Authors: Wiechmann, Tobias, Röh, Simone, Sauer, Susann, Czamara, Darina, Arloth, Janine, Ködel, Maik, Beintner, Madita, Knop, Lisanne, Menke, Andreas, Binder, Elisabeth B., Provençal, Nadine
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6533766/
https://ncbi.nlm.nih.gov/pubmed/31122292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-019-0682-5
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