Glucocorticoid exposure during hippocampal neurogenesis primes future stress response by inducing changes in DNA methylation

Prenatal stress exposure is associated with risk for psychiatric disorders later in life. This may be mediated in part via enhanced exposure to glucocorticoids (GCs), which are known to impact neurogenesis. We aimed to identify molecular mediators of these effects, focusing on long-lasting epigeneti...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Provençal, Nadine, Arloth, Janine, Cattaneo, Annamaria, Anacker, Christoph, Cattane, Nadia, Wiechmann, Tobias, Röh, Simone, Ködel, Maik, Klengel, Torsten, Czamara, Darina, Müller, Nikola S., Lahti, Jari, Räikkönen, Katri, Pariante, Carmine M., Binder, Elisabeth B.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2020
Pynciau:
Biological Embedding Across Timescales Special Feature
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7519233/
https://ncbi.nlm.nih.gov/pubmed/31399550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1820842116
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