Glucocorticoid exposure during hippocampal neurogenesis primes future stress response by inducing changes in DNA methylation

Prenatal stress exposure is associated with risk for psychiatric disorders later in life. This may be mediated in part via enhanced exposure to glucocorticoids (GCs), which are known to impact neurogenesis. We aimed to identify molecular mediators of these effects, focusing on long-lasting epigeneti...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Provençal, Nadine, Arloth, Janine, Cattaneo, Annamaria, Anacker, Christoph, Cattane, Nadia, Wiechmann, Tobias, Röh, Simone, Ködel, Maik, Klengel, Torsten, Czamara, Darina, Müller, Nikola S., Lahti, Jari, Räikkönen, Katri, Pariante, Carmine M., Binder, Elisabeth B.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Biological Embedding Across Timescales Special Feature
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7519233/
https://ncbi.nlm.nih.gov/pubmed/31399550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1820842116
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