Inhibition of FASN suppresses the malignant biological behavior of non-small cell lung cancer cells via deregulating glucose metabolism and AKT/ERK pathway

BACKGROUND: Fatty acid synthase (FASN) is overexpressed in most human carcinomas, including non-small cell lung cancer (NSCLC), and contributes to poor prognosis. An increasing number of studies have highlighted the potential function of FASN as both a biomarker and therapeutic target for cancers. H...

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Vydáno v:Lipids Health Dis
Hlavní autoři: Chang, Ligong, Fang, Surong, Chen, Yubao, Yang, Zhenhua, Yuan, Yuan, Zhang, Jing, Ye, Liang, Gu, Wei
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6533754/
https://ncbi.nlm.nih.gov/pubmed/31122252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12944-019-1058-8
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