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PI3‐kinase/Akt pathway‐regulated membrane transportation of acid‐sensing ion channel 1a/Calcium ion influx/endoplasmic reticulum stress activation on PDGF‐induced HSC Activation
Acid‐sensing ion channel 1a (ASIC1a) allows Na(+) and Ca(2+) flow into cells. It is expressed during inflammation, in tumour and ischaemic tissue, in the central nervous system and non‐neuronal injury environments. Endoplasmic reticulum stress (ERS) is caused by the accumulation of misfolded protein...
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| Опубликовано в: : | J Cell Mol Med |
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| Главные авторы: | , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
John Wiley and Sons Inc.
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6533492/ https://ncbi.nlm.nih.gov/pubmed/30938088 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14275 |
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