PI3‐kinase/Akt pathway‐regulated membrane transportation of acid‐sensing ion channel 1a/Calcium ion influx/endoplasmic reticulum stress activation on PDGF‐induced HSC Activation

Acid‐sensing ion channel 1a (ASIC1a) allows Na(+) and Ca(2+) flow into cells. It is expressed during inflammation, in tumour and ischaemic tissue, in the central nervous system and non‐neuronal injury environments. Endoplasmic reticulum stress (ERS) is caused by the accumulation of misfolded protein...

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Bibliografiske detaljer
Udgivet i:J Cell Mol Med
Main Authors: Zuo, Longquan, Zhu, Yueqin, Hu, Lili, Liu, Yanyi, Wang, Yinghong, Hu, Yamin, Wang, Huan, Pan, Xuesheng, Li, Kuayue, Du, Na, Huang, Yan
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
Fag:
Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6533492/
https://ncbi.nlm.nih.gov/pubmed/30938088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14275
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