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Therapeutic advances for blocking heterotopic ossification in fibrodysplasia ossificans progressiva

Fibrodysplasia ossificans progressiva (FOP) is a rare genetic disease in which heterotopic bone forms in muscle and soft tissue, leading to joint dysfunction and significant disability. FOP is progressive and many patients are wheelchair‐bound by the 3rd decade of life. FOP is caused by an activatin...

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Foilsithe in:Br J Clin Pharmacol
Main Authors: Wentworth, Kelly L., Masharani, Umesh, Hsiao, Edward C.
Formáid: Artigo
Teanga:Inglês
Foilsithe: John Wiley and Sons Inc. 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6533435/
https://ncbi.nlm.nih.gov/pubmed/30501012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13823
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