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Therapeutic advances for blocking heterotopic ossification in fibrodysplasia ossificans progressiva

Fibrodysplasia ossificans progressiva (FOP) is a rare genetic disease in which heterotopic bone forms in muscle and soft tissue, leading to joint dysfunction and significant disability. FOP is progressive and many patients are wheelchair‐bound by the 3rd decade of life. FOP is caused by an activatin...

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Detalhes bibliográficos
Publicado no:Br J Clin Pharmacol
Main Authors: Wentworth, Kelly L., Masharani, Umesh, Hsiao, Edward C.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6533435/
https://ncbi.nlm.nih.gov/pubmed/30501012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13823
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