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ATAC-seq reveals alterations in open chromatin in pancreatic islets from subjects with type 2 diabetes
Impaired insulin secretion from pancreatic islets is a hallmark of type 2 diabetes (T2D). Altered chromatin structure may contribute to the disease. We therefore studied the impact of T2D on open chromatin in human pancreatic islets. We used assay for transposase-accessible chromatin using sequencin...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6533306/ https://ncbi.nlm.nih.gov/pubmed/31123324 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-44076-8 |
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