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Separating host and microbiome contributions to drug pharmacokinetics and toxicity
The gut microbiota is implicated in the metabolism of many medical drugs, with consequences for interpersonal variation in drug efficacy and toxicity. However, quantifying microbial contributions to drug metabolism is challenging, particularly in cases where host and microbiome perform the same meta...
Guardat en:
| Publicat a: | Science |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6533120/ https://ncbi.nlm.nih.gov/pubmed/30733391 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aat9931 |
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