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Separating host and microbiome contributions to drug pharmacokinetics and toxicity
The gut microbiota is implicated in the metabolism of many medical drugs, with consequences for interpersonal variation in drug efficacy and toxicity. However, quantifying microbial contributions to drug metabolism is challenging, particularly in cases where host and microbiome perform the same meta...
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| 出版年: | Science |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6533120/ https://ncbi.nlm.nih.gov/pubmed/30733391 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aat9931 |
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