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Enhanced flux prediction by integrating relative expression and relative metabolite abundance into thermodynamically consistent metabolic models

The ever-increasing availability of transcriptomic and metabolomic data can be used to deeply analyze and make ever-expanding predictions about biological processes, as changes in the reaction fluxes through genome-wide pathways can now be tracked. Currently, constraint-based metabolic modeling appr...

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Bibliografiske detaljer
Udgivet i:PLoS Comput Biol
Main Authors: Pandey, Vikash, Hadadi, Noushin, Hatzimanikatis, Vassily
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6532942/
https://ncbi.nlm.nih.gov/pubmed/31083653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007036
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