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MMP14-Containing Exosomes Cleave VEGFR1 and Promote VEGFA-Induced Migration and Proliferation of Vascular Endothelial Cells
PURPOSE: Investigate the impact matrix metalloproteinase 14 (MMP14) delivered via exosomes produced by corneal fibroblasts on vascular endothelial growth factor receptor 1 (VEGFR1) cleavage on endothelial cells, and other key processes of angiogenesis. METHODS: Proteolysis of VEGFR1 and R2 by the ca...
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| Publicat a: | Invest Ophthalmol Vis Sci |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Association for Research in Vision and Ophthalmology
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6532701/ https://ncbi.nlm.nih.gov/pubmed/31117124 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.18-26277 |
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