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Structure-Activity Relationship Analysis of YM155 for Inducing Selective Cell Death of Human Pluripotent Stem Cells

Despite great potential for regenerative medicine, the high tumorigenic potential of human pluripotent stem cells (hPSCs) to form undesirable teratoma is an important technical hurdle preventing safe cell therapy. Various small molecules that induce the complete elimination of undifferentiated hPSCs...

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Bibliografiske detaljer
Udgivet i:Front Chem
Main Authors: Go, Young-Hyun, Lim, Changjin, Jeong, Ho-Chang, Kwon, Ok-Seon, Chung, Sungkyun, Lee, Haeseung, Kim, Wankyu, Suh, Young-Ger, Son, Woo Sung, Lee, Mi-Ok, Cha, Hyuk-Jin, Kim, Seok-Ho
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6532689/
https://ncbi.nlm.nih.gov/pubmed/31157201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2019.00298
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