Structure-Activity Relationship Analysis of YM155 for Inducing Selective Cell Death of Human Pluripotent Stem Cells

Despite great potential for regenerative medicine, the high tumorigenic potential of human pluripotent stem cells (hPSCs) to form undesirable teratoma is an important technical hurdle preventing safe cell therapy. Various small molecules that induce the complete elimination of undifferentiated hPSCs...

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Bibliographic Details
Published in:Front Chem
Main Authors: Go, Young-Hyun, Lim, Changjin, Jeong, Ho-Chang, Kwon, Ok-Seon, Chung, Sungkyun, Lee, Haeseung, Kim, Wankyu, Suh, Young-Ger, Son, Woo Sung, Lee, Mi-Ok, Cha, Hyuk-Jin, Kim, Seok-Ho
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2019
Subjects:
Chemistry
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6532689/
https://ncbi.nlm.nih.gov/pubmed/31157201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2019.00298
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