Transcriptional consequences of impaired immune cell responses induced by cystic fibrosis plasma characterized via dual RNA sequencing

BACKGROUND: In cystic fibrosis (CF), impaired immune cell responses, driven by the dysfunctional CF transmembrane conductance regulator (CFTR) gene, may determine the disease severity but clinical heterogeneity remains a major therapeutic challenge. The characterization of molecular mechanisms under...

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Vydáno v:BMC Med Genomics
Hlavní autoři: Ideozu, Justin E., Rangaraj, Vittobai, Abdala-Valencia, Hiam, Zhang, Xi, Kandpal, Manoj, Sala, Marc A., Davuluri, Ramana V., Levy, Hara
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6532208/
https://ncbi.nlm.nih.gov/pubmed/31118097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-019-0529-0
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