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The C-Terminal End of HIV-1 Vpu Has a Clade-Specific Determinant That Antagonizes BST-2 and Facilitates Virion Release

The cellular protein bone marrow stromal antigen-2 (BST-2)/tetherin acts against a variety of enveloped viruses by restricting their release from the plasma membrane. The HIV-1 accessory protein Vpu counteracts BST-2 by downregulating it from the cell surface and displacing it from virion assembly s...

詳細記述

保存先:
書誌詳細
出版年:J Virol
主要な著者: Sharma, Shilpi, Jafari, Moein, Bangar, Amandip, William, Karen, Guatelli, John, Lewinski, Mary K.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6532089/
https://ncbi.nlm.nih.gov/pubmed/30867310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02315-18
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