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High Content, Phenotypic Assays and Screens for Compounds Modulating Cellular Processes in Primary Neurons

High content, phenotypic screens offer a powerful approach to systems biology at the cellular level. The approach employs cells carrying fluorescently-labeled molecules or organelles in 384 or 1536 well microplates, and an automated confocal screening microscope for capturing images from each well....

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Bibliografiske detaljer
Udgivet i:Methods Enzymol
Main Authors: Kepiro, Miklos, Varkuti, Boglarka H., Davis, Ronald L.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6532062/
https://ncbi.nlm.nih.gov/pubmed/30390800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2018.09.021
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