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Mechanisms of CD8+ T cell-mediated suppression of HIV/SIV replication

In this article, we summarize the role of CD8+ T cells during natural and ART-treated HIV and SIV infections, discuss the mechanisms responsible for their suppressive activity, and review the rationale for CD8+ T cell-based HIV cure strategies. Evidence suggests that CD8+ T cells are involved in the...

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Bibliographic Details
Published in:Eur J Immunol
Main Authors: McBrien, Julia Bergild, Kumar, Nitasha A, Silvestri, Guido
Format: Artigo
Language:Inglês
Published: 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6531861/
https://ncbi.nlm.nih.gov/pubmed/29427516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201747172
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