The phosphodiesterase 5 inhibitor sildenafil decreases the proinflammatory chemokine IL-8 in diabetic cardiomyopathy: in vivo and in vitro evidence

PURPOSE: Interleukin (IL)-8 is a proinflammatory C-X-C chemokine involved in inflammation underling cardiac diseases, primary or in comorbid condition, such diabetic cardiomyopathy (DCM). The phosphodiesterase type 5 inhibitor sildenafil can ameliorate cardiac conditions by counteracting inflammatio...

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Publicat a:J Endocrinol Invest
Autors principals: Giannattasio, S., Corinaldesi, C., Colletti, M., Di Luigi, L., Antinozzi, C., Filardi, T., Scolletta, S., Basili, S., Lenzi, A., Morano, S., Crescioli, C.
Format: Artigo
Idioma:Inglês
Publicat: Springer International Publishing 2018
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6531405/
https://ncbi.nlm.nih.gov/pubmed/30415310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40618-018-0977-y
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