Rapid microarray-based assay for detection of pyrazinamide resistant Mycobacterium tuberculosis

Pyrazinamide (PZA) is a key antibiotic for the treatment of drug susceptible tuberculosis. PZA-resistance is mainly mediated by mutations in the pncA gene; however the current gold standard is a phenotypic drug susceptibility test requiring a well-adjusted pH-value for reliable results. Our melting...

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Bibliografiska uppgifter
I publikationen:Diagn Microbiol Infect Dis
Huvudupphovsmän: Havlicek, Juliane, Dachsel, Beatrice, Slickers, Peter, Andres, Sönke, Beckert, Patrick, Feuerriegel, Silke, Niemann, Stefan, Merker, Matthias, Labugger, Ines
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier Biomedical 2019
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6531379/
https://ncbi.nlm.nih.gov/pubmed/30733004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.diagmicrobio.2018.12.011
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