Sonic hedgehog pathway activation is associated with cetuximab resistance and EPHB3 receptor induction in colorectal cancer

A major problem of colorectal cancer (CRC) targeted therapies is relapse caused by drug resistance. In most cases of CRC, patients develop resistance to anticancer drugs. Cetuximab does not show many of the side effects of other anticancer drugs and improves the survival of patients with metastatic...

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Dettagli Bibliografici
Pubblicato in:Theranostics
Autori principali: Park, Seong Hye, Jo, Min Jee, Kim, Bo Ram, Jeong, Yoon A, Na, Yoo Jin, Kim, Jung Lim, Jeong, Soyeon, Yun, Hye Kyeong, Kim, Dae Yeong, Kim, Bu Gyeom, Kang, Sang Hee, Oh, Sang Cheul, Lee, Dae-Hee
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ivyspring International Publisher 2019
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6531304/
https://ncbi.nlm.nih.gov/pubmed/31149041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.30678
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