RUNX3 suppresses metastasis and stemness by inhibiting Hedgehog signaling in colorectal cancer

Disabled tumor suppressor genes and hyperactive oncogenes greatly contribute to cell fates during cancer development because of their genetic alterations such as somatic mutations. However, little is known about how tumor suppressor genes react to diverse oncogenes during tumor progression. Our prev...

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Vydáno v:Cell Death Differ
Hlavní autoři: Kim, Bo Ram, Na, Yoo Jin, Kim, Jung Lim, Jeong, Yoon A., Park, Seong Hye, Jo, Min Jee, Jeong, Soyeon, Kang, Sanghee, Oh, Sang Cheul, Lee, Dae-Hee
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7205901/
https://ncbi.nlm.nih.gov/pubmed/31278361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-019-0379-5
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