Human LAP(+)GARP(+)FOXP3(+) regulatory T cells attenuate xenogeneic graft versus host disease

Adoptive transfer of regulatory T cells (FOXP3(+) Tregs) has been developed as a potential curative immune therapy to prevent and treat autoimmune and graft-versus-host diseases (GVHD). A major limitation that has hindered the use of Treg immunotherapy in humans is the difficulty of consistently iso...

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Bibliographische Detailangaben
Veröffentlicht in:Theranostics
Hauptverfasser: Wang, Huihui, Song, Hyo, Pham, Anha V., Cooper, Laurence J., Schulze, Janika J., Olek, Sven, Tran, Dat Q.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ivyspring International Publisher 2019
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6531299/
https://ncbi.nlm.nih.gov/pubmed/31149046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.30254
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