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Generation of lung organoids from human pluripotent stem cells in vitro

The lung epithelium is derived from the endodermal germ layer, which undergoes a complex series of endoderm–mesoderm-mediated signaling events to generate the final arborized network of conducting airways (bronchi, bronchioles) and gas-exchanging units (alveoli). These stages include endoderm induct...

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Detalhes bibliográficos
Publicado no:Nat Protoc
Main Authors: Miller, Alyssa J., Dye, Briana R., Ferrer-Torres, Daysha, Hill, David R., Overeem, Arend W., Shea, Lonnie D., Spence, Jason R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6531049/
https://ncbi.nlm.nih.gov/pubmed/30664680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41596-018-0104-8
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