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A bioengineered niche promotes in vivo engraftment and maturation of pluripotent stem cell derived human lung organoids

Human pluripotent stem cell (hPSC) derived tissues often remain developmentally immature in vitro, and become more adult-like in their structure, cellular diversity and function following transplantation into immunocompromised mice. Previously we have demonstrated that hPSC-derived human lung organo...

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Detalles Bibliográficos
Publicado en:eLife
Main Authors: Dye, Briana R, Dedhia, Priya H, Miller, Alyssa J, Nagy, Melinda S, White, Eric S, Shea, Lonnie D, Spence, Jason R
Formato: Artigo
Idioma:Inglês
Publicado: eLife Sciences Publications, Ltd 2016
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5089859/
https://ncbi.nlm.nih.gov/pubmed/27677847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.19732
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