A bioengineered niche promotes in vivo engraftment and maturation of pluripotent stem cell derived human lung organoids

Human pluripotent stem cell (hPSC) derived tissues often remain developmentally immature in vitro, and become more adult-like in their structure, cellular diversity and function following transplantation into immunocompromised mice. Previously we have demonstrated that hPSC-derived human lung organo...

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Bibliographic Details
Published in:eLife
Main Authors: Dye, Briana R, Dedhia, Priya H, Miller, Alyssa J, Nagy, Melinda S, White, Eric S, Shea, Lonnie D, Spence, Jason R
Format: Artigo
Language:Inglês
Published: eLife Sciences Publications, Ltd 2016
Subjects:
Developmental Biology and Stem Cells
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5089859/
https://ncbi.nlm.nih.gov/pubmed/27677847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.19732
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