A bioengineered niche promotes in vivo engraftment and maturation of pluripotent stem cell derived human lung organoids

Human pluripotent stem cell (hPSC) derived tissues often remain developmentally immature in vitro, and become more adult-like in their structure, cellular diversity and function following transplantation into immunocompromised mice. Previously we have demonstrated that hPSC-derived human lung organo...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Dye, Briana R, Dedhia, Priya H, Miller, Alyssa J, Nagy, Melinda S, White, Eric S, Shea, Lonnie D, Spence, Jason R
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2016
Assuntos:
Developmental Biology and Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5089859/
https://ncbi.nlm.nih.gov/pubmed/27677847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.19732
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