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Ti-Catalyzed Radical Alkylation of Secondary and Tertiary Alkyl Chlorides Using Michael Acceptors

Alkyl chlorides are common functional groups in synthetic organic chemistry. However, the engagement of unactivated alkyl chlorides, especially tertiary alkyl chlorides, in transition-metal-catalyzed C–C bond formation remains challenging. Herein, we describe the development of a Ti(III)-catalyzed r...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Wu, Xiangyu, Hao, Wei, Ye, Ke-Yin, Jiang, Binyang, Pombar, Gisselle, Song, Zhidong, Lin, Song
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6530901/
https://ncbi.nlm.nih.gov/pubmed/30303379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b08605
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