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Actin Dynamics, Regulated by RhoA-LIMK-Cofilin Signaling, Mediates Rod Photoreceptor Axonal Retraction After Retinal Injury

PURPOSE: Retraction of the axon terminals of rod photoreceptors after retinal detachment breaks the first synapse in the visual pathway, resulting in visual impairment. Previous work showed that the mechanism of axonal retraction involves RhoA signaling and its downstream effector LIM Kinase (LIMK)...

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Bibliografski detalji
Izdano u:Invest Ophthalmol Vis Sci
Glavni autori: Wang, Weiwei, Halasz, Eva, Townes-Anderson, Ellen
Format: Artigo
Jezik:Inglês
Izdano: The Association for Research in Vision and Ophthalmology 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6530517/
https://ncbi.nlm.nih.gov/pubmed/31112612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.18-26077
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