Actin Dynamics, Regulated by RhoA-LIMK-Cofilin Signaling, Mediates Rod Photoreceptor Axonal Retraction After Retinal Injury

PURPOSE: Retraction of the axon terminals of rod photoreceptors after retinal detachment breaks the first synapse in the visual pathway, resulting in visual impairment. Previous work showed that the mechanism of axonal retraction involves RhoA signaling and its downstream effector LIM Kinase (LIMK)...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Invest Ophthalmol Vis Sci
Prif Awduron: Wang, Weiwei, Halasz, Eva, Townes-Anderson, Ellen
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Association for Research in Vision and Ophthalmology 2019
Pynciau:
Retina
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6530517/
https://ncbi.nlm.nih.gov/pubmed/31112612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.18-26077
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg