Hemagglutinin-neuraminidase and fusion proteins of virulent Newcastle disease virus cooperatively disturb fusion–fission homeostasis to enhance mitochondrial function by activating the unfolded protein response of endoplasmic reticulum and mitochondrial stress

The fusogenically activated F and HN proteins of virulent NDV induce complete autophagic flux in DF-1 and A549 cells. However, the effect of both glycoproteins on mitochondria remains elusive. Here, we found that F and HN cooperation increases mitochondrial biogenesis but does not cause the mitochon...

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Vydáno v:Vet Res
Hlavní autoři: Ren, Shanhui, Rehman, Zaib Ur, Shi, Mengyu, Yang, Bin, Liu, Panrao, Yin, Yuncong, Qu, Yurong, Meng, Chunchun, Yang, Zengqi, Gao, Xiaolong, Sun, Yingjie, Ding, Chan
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
Short Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6530190/
https://ncbi.nlm.nih.gov/pubmed/31118100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13567-019-0654-y
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