Hemagglutinin-neuraminidase and fusion proteins of virulent Newcastle disease virus cooperatively disturb fusion–fission homeostasis to enhance mitochondrial function by activating the unfolded protein response of endoplasmic reticulum and mitochondrial stress

The fusogenically activated F and HN proteins of virulent NDV induce complete autophagic flux in DF-1 and A549 cells. However, the effect of both glycoproteins on mitochondria remains elusive. Here, we found that F and HN cooperation increases mitochondrial biogenesis but does not cause the mitochon...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Vet Res
Prif Awduron: Ren, Shanhui, Rehman, Zaib Ur, Shi, Mengyu, Yang, Bin, Liu, Panrao, Yin, Yuncong, Qu, Yurong, Meng, Chunchun, Yang, Zengqi, Gao, Xiaolong, Sun, Yingjie, Ding, Chan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2019
Pynciau:
Short Report
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6530190/
https://ncbi.nlm.nih.gov/pubmed/31118100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13567-019-0654-y
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