Hemagglutinin-neuraminidase and fusion proteins of virulent Newcastle disease virus cooperatively disturb fusion–fission homeostasis to enhance mitochondrial function by activating the unfolded protein response of endoplasmic reticulum and mitochondrial stress

The fusogenically activated F and HN proteins of virulent NDV induce complete autophagic flux in DF-1 and A549 cells. However, the effect of both glycoproteins on mitochondria remains elusive. Here, we found that F and HN cooperation increases mitochondrial biogenesis but does not cause the mitochon...

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Dettagli Bibliografici
Pubblicato in:Vet Res
Autori principali: Ren, Shanhui, Rehman, Zaib Ur, Shi, Mengyu, Yang, Bin, Liu, Panrao, Yin, Yuncong, Qu, Yurong, Meng, Chunchun, Yang, Zengqi, Gao, Xiaolong, Sun, Yingjie, Ding, Chan
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
Soggetti:
Short Report
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6530190/
https://ncbi.nlm.nih.gov/pubmed/31118100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13567-019-0654-y
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