Beneficial Metabolic Effects of Mirabegron In Vitro and in High-Fat Diet-Induced Obese Mice

Mirabegron, a β3-adrenergic receptor agonist, has been shown to stimulate the activity of brown fat and increase the resting metabolic rate in humans. However, it is unknown whether mirabegron can reduce body weight and improve metabolic health. We investigated the antiobesity effects of mirabegron...

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Vydáno v:J Pharmacol Exp Ther
Hlavní autoři: Hao, Lei, Scott, Sheyenne, Abbasi, Mehrnaz, Zu, Yujiao, Khan, Md Shahjalal Hossain, Yang, Yang, Wu, Dayong, Zhao, Ling, Wang, Shu
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Pharmacology and Experimental Therapeutics 2019
Témata:
Drug Discovery and Translational Medicine
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6530071/
https://ncbi.nlm.nih.gov/pubmed/30940691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.118.255778
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