Indomethacin Enhances Brown Fat Activity

Indomethacin, a nonsteroidal anti-inflammatory drug, has been shown to induce white adipocyte differentiation; however, its roles in brown adipocyte differentiation and activation in brown adipose tissue (BAT) and obesity are unknown. To address this issue, we treated mouse brown preadipocytes with...

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Vydáno v:J Pharmacol Exp Ther
Hlavní autoři: Hao, Lei, Kearns, Jamie, Scott, Sheyenne, Wu, Dayong, Kodani, Sean D., Morisseau, Christophe, Hammock, Bruce D., Sun, Xiaocun, Zhao, Ling, Wang, Shu
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Pharmacology and Experimental Therapeutics 2018
Témata:
Drug Discovery and Translational Medicine
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5931432/
https://ncbi.nlm.nih.gov/pubmed/29567865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.117.246256
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