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Farnesyl pyrophosphate synthase is essential for the promastigote and amastigote stages in Leishmania major

Isoprenoid synthesis provides a diverse class of biomolecules including sterols, dolichols, ubiquinones and prenyl groups. The enzyme farnesyl pyrophosphate synthase (FPPS) catalyzes the formation of farnesyl pyrophosphate, a key intermediate for the biosynthesis of all isoprenoids. In Leishmania, F...

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Detalhes bibliográficos
Publicado no:Mol Biochem Parasitol
Main Authors: Mukherjee, Sumit, Basu, Somrita, Zhang, Kai
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6529949/
https://ncbi.nlm.nih.gov/pubmed/30926449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molbiopara.2019.03.001
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