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The Second Messenger c-di-AMP Regulates Diverse Cellular Pathways Involved in Stress Response, Biofilm Formation, Cell Wall Homeostasis, SpeB Expression, and Virulence in Streptococcus pyogenes

Cyclic di-AMP (c-di-AMP) is a recently discovered second messenger in bacteria. The cellular level of c-di-AMP in Streptococcus pyogenes is predicted to be controlled by the synthase DacA and two putative phosphodiesterases, GdpP and Pde2. To investigate the role of c-di-AMP in S. pyogenes, we gener...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Fahmi, Tazin, Faozia, Sabrina, Port, Gary C., Cho, Kyu Hong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6529668/
https://ncbi.nlm.nih.gov/pubmed/30936159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00147-19
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