Prediction and Validation of Immunogenic Domains of Pneumococcal Proteins Recognized by Human CD4(+) T Cells

CD4(+) T-cell mechanisms are implied in protection against pneumococcal colonization; however, their target antigens and function are not well defined. In contrast to high-throughput protein arrays for serology, basic antigen tools for CD4(+) T-cell studies are lacking. Here, we evaluate the potenti...

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Detalles Bibliográficos
Publicado en:Infect Immun
Main Authors: van de Garde, Martijn D. B., van Westen, Els, Poelen, Martien C. M., Rots, Nynke Y., van Els, Cécile A. C. M.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2019
Assuntos:
Microbial Immunity and Vaccines
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6529658/
https://ncbi.nlm.nih.gov/pubmed/30910792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00098-19
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