Immunodominance in T cell responses elicited against different domains of detoxified pneumolysin PlyD1

Detoxified pneumolysin, PlyD1, is a protein vaccine candidate that induces protection against infections with Streptococcus pneumoniae in mouse models. Despite extensive knowledge on antibody responses against PlyD1, limited information is available about PlyD1 induced T cell recognition. Here we in...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: van Westen, Els, Poelen, Martien C. M., van den Dobbelsteen, Germie P. J. M., Oloo, Eliud O., Ochs, Martina M., Rots, Nynke Y., van Els, Cecile A. C. M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5839544/
https://ncbi.nlm.nih.gov/pubmed/29509778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0193650
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