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Tapentadol in the treatment of osteoarthritis: pharmacological rationale and clinical evidence

Osteoarthritis (OA) is the most prevalent joint disease in older people worldwide. Pain owing to OA is considered one of the most frequent causes of chronic pain; however, current pharmacological approaches have some limitations in terms of efficacy and safety. Of note, descending inhibitory pain pa...

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Publicado en:J Pain Res
Autores principales: Rinonapoli, Giuseppe, Coaccioli, Stefano, Panella, Lorenzo
Formato: Artigo
Lenguaje:Inglês
Publicado: Dove 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6529616/
https://ncbi.nlm.nih.gov/pubmed/31190964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JPR.S190161
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