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Pharmacology and rationale for imatinib in the treatment of scleroderma

Systemic sclerosis (scleroderma) is a chronic, multisystem, fibrotic disease. Although the pathogenesis is not completely understood, early vascular damage leads to an inflammatory reaction and a severe fibrotic response. Therapy of systemic sclerosis is still not convincing and is mainly restricted...

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Detalhes bibliográficos
Publicado no:J Exp Pharmacol
Main Authors: Moinzadeh, Pia, Hunzelmann, Nicolas, Krieg, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4863537/
https://ncbi.nlm.nih.gov/pubmed/27186133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JEP.S26894
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