Adjacent intact nociceptive neurons drive the acute outburst of pain following peripheral axotomy

Injury of peripheral nerves may quickly induce severe pain, but the mechanism remains obscure. We observed a rapid onset of spontaneous pain and evoked pain hypersensitivity after acute transection of the L5 spinal nerve (SNT) in awake rats. The outburst of pain was associated with a rapid developme...

Full description

Saved in:
Bibliographic Details
Published in:Sci Rep
Main Authors: Chen, Zhiyong, Wang, Tao, Fang, Yehong, Luo, Dan, Anderson, Michael, Huang, Qian, He, Shaoqiu, Song, Xiaodan, Cui, Huan, Dong, Xinzhong, Xie, Yikuan, Guan, Yun, Ma, Chao
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6529466/
https://ncbi.nlm.nih.gov/pubmed/31113988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-44172-9
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items