Down-regulation of MEIS1 promotes the maturation of oxidative phosphorylation in perinatal cardiomyocytes

Fetal cardiomyocytes shift from glycolysis to oxidative phosphorylation around the time of birth. Myeloid ecotropic viral integration site 1 (MEIS1) is a transcription factor that promotes glycolysis in hematopoietic stem cells. We reasoned that MEIS1 could have a similar role in the developing hear...

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Bibliographic Details
Published in:FASEB J
Main Authors: Lindgren, Isa M., Drake, Rachel R., Chattergoon, Natasha N., Thornburg, Kent L.
Format: Artigo
Language:Inglês
Published: Federation of American Societies for Experimental Biology 2019
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6529342/
https://ncbi.nlm.nih.gov/pubmed/30884246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201801330RR
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