Thyroid hormone drives fetal cardiomyocyte maturation

Tri-iodo-l-thyronine (T(3)) suppresses the proliferation of near-term serum-stimulated fetal ovine cardiomyocytes in vitro. Thus, we hypothesized that T(3) is a major stimulant of cardiomyocyte maturation in vivo. We studied 3 groups of sheep fetuses on gestational days 125–130 (term ∼145 d): a T(3)...

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Bibliografiske detaljer
Main Authors: Chattergoon, Natasha N., Giraud, George D., Louey, Samantha, Stork, Philip, Fowden, Abigail L., Thornburg, Kent L.
Format: Artigo
Sprog:Inglês
Udgivet: Federation of American Societies for Experimental Biology 2012
Fag:
Research Communications
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3250248/
https://ncbi.nlm.nih.gov/pubmed/21974928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.10-179895
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