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Thyroid hormone drives fetal cardiomyocyte maturation
Tri-iodo-l-thyronine (T(3)) suppresses the proliferation of near-term serum-stimulated fetal ovine cardiomyocytes in vitro. Thus, we hypothesized that T(3) is a major stimulant of cardiomyocyte maturation in vivo. We studied 3 groups of sheep fetuses on gestational days 125–130 (term ∼145 d): a T(3)...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Federation of American Societies for Experimental Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3250248/ https://ncbi.nlm.nih.gov/pubmed/21974928 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.10-179895 |
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