B-lymphocyte–intrinsic and –extrinsic defects in secretory immunoglobulin A production in the neural crest–conditional deletion of endothelin receptor B model of Hirschsprung-associated enterocolitis

Hirschsprung disease (HSCR) is a common cause of intestinal obstruction in the newborn. Hirschsprung-associated enterocolitis (HAEC) is a significant and life-threatening complication of HSCR, affecting up to 60% of patients. Animal models of endothelin receptor B (EdnrB) mutation reliably model hum...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Medrano, Giuliana, Cailleux, Frederic, Guan, Peihong, Kuruvilla, Korah, Barlow-Anacker, Amanda J., Gosain, Ankush
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6529339/
https://ncbi.nlm.nih.gov/pubmed/30908942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201801913R
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