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A Legionella pneumophila kinase phosphorylates the Hsp70 chaperone family to inhibit eukaryotic protein synthesis
Legionella pneumophila (L.p.), the microbe responsible for Legionnaires’ disease, secretes ~300 bacterial proteins into the host cell cytosol. A subset of these proteins affect a wide range of post-translational modifications (PTMs) to disrupt host cellular pathways. L.p. has 5 conserved eukaryotic-...
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| Publicado en: | Cell Host Microbe |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6529236/ https://ncbi.nlm.nih.gov/pubmed/30827827 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2019.01.006 |
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