Higher-Order Clustering of the Transmembrane Anchor of DR5 Drives Signaling

Receptor clustering on cell membrane is critical in the signaling of many immunoreceptors and this mechanism has previously been attributed to the extracellular and/or the intracellular interactions. Here, we report an unexpected finding that for death receptor 5 (DR5), a receptor in the tumor necro...

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Publicado no:Cell
Main Authors: Pan, Liqiang, Fu, Tian-Min, Zhao, Wenbin, Zhao, Linlin, Chen, Wen, Qiu, Chixiao, Liu, Wenhui, Liu, Zhijun, Piai, Alessandro, Fu, Qingshan, Chen, Shuqing, Wu, Hao, Chou, James J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6529188/
https://ncbi.nlm.nih.gov/pubmed/30827683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2019.02.001
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