Depression Promotes the Onset of Irritable Bowel Syndrome through Unique Dysbiosis in Rats

BACKGROUND/AIMS: Although studies using conventional animal models have shown that specific stressors cause irritable bowel syndrome (IBS), it is unclear whether depression itself causes IBS. Our aim was to establish a rat model to determine if depression itself promotes the onset of IBS and to eluc...

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Publicat a:Gut Liver
Autors principals: Takajo, Takeshi, Tomita, Kengo, Tsuchihashi, Hanae, Enomoto, Shingo, Tanichi, Masaaki, Toda, Hiroyuki, Okada, Yoshikiyo, Furuhashi, Hirotaka, Sugihara, Nao, Wada, Akinori, Horiuchi, Kazuki, Inaba, Kenichi, Hanawa, Yoshinori, Shibuya, Naoki, Shirakabe, Kazuhiko, Higashiyama, Masaaki, Kurihara, Chie, Watanabe, Chikako, Komoto, Shunsuke, Nagao, Shigeaki, Kimura, Katsunori, Miura, Soichiro, Shimizu, Kunio, Hokari, Ryota
Format: Artigo
Idioma:Inglês
Publicat: Editorial Office of Gut and Liver 2019
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6529174/
https://ncbi.nlm.nih.gov/pubmed/30602220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5009/gnl18296
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