Chitinase 3‐like 1 deficiency ameliorates liver fibrosis by promoting hepatic macrophage apoptosis

AIM: Chitinase 3‐like 1 (CHI3L1), an 18‐glycosyl hydrolase‐related molecule, is a member of the enzymatically inactive chitinase‐like protein family. Serum levels of CHI3L1 are strongly correlated with hepatic fibrosis progression during many liver diseases. Therefore, this protein could be involved...

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Bibliografiske detaljer
Udgivet i:Hepatol Res
Main Authors: Higashiyama, Masaaki, Tomita, Kengo, Sugihara, Nao, Nakashima, Hiroyuki, Furuhashi, Hirotaka, Nishikawa, Makoto, Inaba, Kenichi, Wada, Akinori, Horiuchi, Kazuki, Hanawa, Yoshinori, Shibuya, Naoki, Kurihara, Chie, Okada, Yoshikiyo, Nishii, Shin, Mizoguchi, Akinori, Hozumi, Hideaki, Watanabe, Chikako, Komoto, Shunsuke, Yamamoto, Junji, Seki, Shuhji, Miura, Soichiro, Hokari, Ryota
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6916176/
https://ncbi.nlm.nih.gov/pubmed/31250532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/hepr.13396
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