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Bone marrow endothelial progenitor cells activate hepatic stellate cells and aggravate carbon tetrachloride induced liver fibrosis in mice via paracrine factors

OBJECTIVES: Bone marrow derived endothelial progenitor cells (BM‐EPCs) are increased in chronic liver disease (CLD). Their role in hepatic fibrosis and regeneration remains an area of intense studies. We investigated the migration and secretory functions of BM‐EPCs in fibrotic mice liver. MATERIALS...

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Detalhes bibliográficos
Publicado no:Cell Prolif
Main Authors: Garg, Manali, Kaur, Savneet, Banik, Arpita, Kumar, Vikash, Rastogi, Archana, Sarin, Shiv K., Mukhopadhyay, Asok, Trehanpati, Nirupma
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6529081/
https://ncbi.nlm.nih.gov/pubmed/28682508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.12355
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