Blockade of Neutrophil’s Chemokine Receptors CXCR1/2 Abrogate Liver Damage in Acute-on-Chronic Liver Failure

BACKGROUND: Neutrophils serve as critical players in the pathogenesis of liver diseases. Chemokine receptors CXCR1 and CXCR2 are required for neutrophil chemotaxis to the site of inflammation/injury and are crucial in hepatic inflammatory response. However, key mechanism of neutrophil-mediated liver...

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Publicado en:Front Immunol
Autores principales: Khanam, Arshi, Trehanpati, Nirupma, Riese, Peggy, Rastogi, Archana, Guzman, Carlos Alberto, Sarin, Shiv Kumar
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5401894/
https://ncbi.nlm.nih.gov/pubmed/28484461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00464
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